Rebound Headache - Symptoms & Causes

What is a rebound headache? 

A rebound headache, also known as a medication-overuse headache, occurs when the frequent use of headache medications leads to a cycle of recurring headaches. This condition typically arises when pain relief medications are used more than a few times a week.  

Instead of alleviating headache symptoms, the overuse of these medications can cause headaches to return as soon as the medication wears off, prompting further medication use and perpetuating the cycle. 

What are the types of rebound headaches? 

Rebound headaches can be classified based on the type of medication overused: 

  • Analgesic overuse headache, triggered by the frequent use of pain relievers such as aspirin, ibuprofen, or acetaminophen. 
  • Combination medication overuse headache, caused by the overuse of medications that combine pain relievers with caffeine or other ingredients. 
  • Triptan overuse headache, resulting from the excessive use of triptans, a class of drugs used to treat migraines. 
  • Opioid overuse headache, stemming from the overuse of opioid medications for pain relief.

What are the symptoms of a rebound headache? 

Symptoms of a rebound headache includes: 

  • Daily or almost daily headaches, often exceeding 15 days per month, is a telltale sign 
  • Headache that improves with medication but returns as the medication wears off 
  • Worsening headache despite continued use of medication 
  • Accompanying symptoms such as nausea, irritability, and restlessness 
  • Difficulty concentrating and disrupted sleep patterns 

When to seek medical attention? 

You should seek medical attention if: 

  • You experience frequent headaches that require regular use of pain relief medications (more than 15 days a month) 
  • Your headaches persist despite taking medication 
  • Over-the-counter medications no longer provide effective relief 
  • Your headaches interfere with daily activities and quality of life 

When to visit an urgent care centre? 

Visit an urgent care centre if: 

  • You have a sudden, severe headache that is different from your usual headaches 
  • Your headache is accompanied by symptoms such as fever, confusion, vision changes, or loss of consciousness 
  • You experience neurological symptoms like weakness, numbness, or difficulty speaking

What causes a rebound headache?

Rebound headaches are caused by the regular overuse of headache medications. This overuse alters pain pathways and receptors in the brain, making them more sensitive to pain signals. When the effects of the medication wear off, withdrawal symptoms can trigger another headache, leading to a cycle of medication overuse and recurring headaches. Common medications that can cause rebound headaches include:

  • Over-the-counter pain relievers (aspirin, ibuprofen, acetaminophen)
  • Combination medications containing caffeine or other ingredients
  • Prescription medications such as triptans and opioids

What are the complications of a rebound headache? 

Rebound headaches themselves are not life-threatening, but they can cause some significant complications that affect your quality of life:  

  • Chronic daily headaches 
  • Increased dependency on medications 
  • Reduced effectiveness of headache treatments 
  • Decreased quality of life due to persistent pain and associated symptoms 
  • Potential for medication side effects and adverse reactions 
  • Impact on mental health

How do you prevent rebound headaches? 

Preventing rebound headaches involves managing medication use and adopting healthy headache management strategies: 

  • Use headache medications only as directed and limit their use to no more than two to three times a week. 
  • Work with your healthcare provider to develop a headache management plan that includes preventive treatments and lifestyle changes. 
  • Explore non-medication strategies like applying a cold compress, getting adequate sleep, practicing relaxation techniques, and staying hydrated. 
  • Adopt a healthy lifestyle that includes regular exercise, a balanced diet, adequate sleep, and stress management techniques. 

If you have chronic headaches, consult your doctor to identify and address any underlying causes. This can help reduce your reliance on pain relievers in the long run.

This page has been reviewed by our medical content reviewers.

Need help?


For appointment bookings, please Whatsapp
+65 8198 7777

For clinic or corporate matters, please call
+65 6227 7777